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The classification of oximetry signals using Bayesian neural networks to assist in the detection of obstructive sleep apnoea syndrome

机译:使用贝叶斯神经网络对血氧饱和度信号进行分类,以帮助检测阻塞性睡眠呼吸暂停综合症

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In the present study,multilayer perceptron (MLP) neural networkswere applied to help in the diagnosis of obstructive sleep apnoea syndrome (OSAS). Oxygen saturation (SaO2) recordings from nocturnal pulse oximetry were used for this purpose. We performed time and spectral analysis of these signals to extract 14 features related to OSAS. The performance of two different MLP classifiers was compared: maximum likelihood (ML) and Bayesian (BY) MLP networks. A total of 187 subjects suspected of suffering from OSAS took part in the study. Their SaO2 signals were divided into a training set with 74 recordings and a test set with 113 recordings. BY-MLP networks achieved the best performance on the test set with 85.58% accuracy (87.76% sensitivity and 82.39% specificity). These results were substantially better than those provided by ML-MLP networks, which were affected by overfitting and achieved an accuracy of 76.81% (86.42% sensitivity and 62.83% specificity). Our results suggest that the Bayesian framework is preferred to i plement our MLP classifiers. The proposed BY-MLP networks could be used for early OSAS detection. They could contribute to overcome the difficulties of nocturnal polysomnography (PSG) and thus reduce the demand for these studies.
机译:在本研究中,多层感知器(MLP)神经网络被用于帮助诊断阻塞性睡眠呼吸暂停综合症(OSAS)。夜间脉搏血氧仪的氧饱和度(SaO2)记录用于此目的。我们对这些信号进行了时间和频谱分析,以提取与OSAS相关的14个特征。比较了两个不同的MLP分类器的性能:最大似然(ML)和贝叶斯(BY)MLP网络。共有187名怀疑患有OSAS的受试者参加了这项研究。他们的SaO2信号分为具有74条记录的训练集和具有113条记录的测试集。 BY-MLP网络以85.58%的准确度(灵敏度为87.76%和特异性为82.39%)在测试仪上获得了最佳性能。这些结果大大优于ML-MLP网络所提供的结果,后者受到过度拟合的影响,并且达到了76.81%的准确度(灵敏度为86.42%,特异性为62.83%)。我们的结果表明,优选贝叶斯框架来实现我们的MLP分类器。提议的BY-MLP网络可用于早期OSAS检测。它们可能有助于克服夜间多导睡眠图(PSG)的困难,从而减少对这些研究的需求。

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