Skin photosensitivity induced by drugs is a side effect that occurs as a consequence of exposure to ultraviolet or visible light. It accounts for 8% of all side effects to drugs.This type of reaction can be classified as photoallergic or phototoxic based on its pathogenesis. Despite a detailed medical record, a good physical examination, a histological study and skin phototest and patch test, in many cases it is not possible to determine whether the skin photosensitivity is due to one mechanism or the other.The drugs that most frequently produce photosensitizing reactions are amiodarone, chlorpomazine, doxycycline, tet-racycline, hydrochlorothiazide, nalidixic acid, naproxen, piroxicam, thioridazine and voriconazole. We present the first case of photosensitivity to lenalidomide (1).
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