Mass spectrometric fragmentation of 2a,4-disubstituted 2,2a,3,4-tetrahydro-2-phenyl-1H-azeto[2,1-d]-[1,5]benzothiazepin-1-ones under electron impact ionization conditions and comparison with their 2-heteroatom substituted analogues

摘要

The mass spectrometric behavior of seven 2a,4-disubstituted-2,2a,3,4-tetraltydro-2phenyl- 1H-azeto[2,1-d][1,5]benzothiazepin-1-ones has been studied with the aid of mass-analyzed ion kinetic energy spectrometry and accurate mass measurements under electron impact ionization. All compounds show a tendency to eliminate a phenylketene molecule, an ethyl or benzyl radical, or a phenylketene molecule plus an SH radical. The mass spectrometric behavior of the title compounds was compared to those of 2-heteroatom-substituted analogues.