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Optimisation of the imaging and dosimetric characteristics of an electronic portal imaging device employing plastic scintillating fibres using Monte Carlo simulations

机译:使用蒙特卡洛模拟优化采用塑料闪烁纤维的电子门禁成像设备的成像和剂量特性

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摘要

A Monte Carlo model of a novel electronic portal imaging device (EPID) has been developed using Geant4 and its performance for imaging and dosimetry applications in radiotherapy has been characterised. The EPID geometry is based on a physical prototype under ongoing investigation and comprises an array of plastic scintillating fibres in place of the metal plate/phosphor screen in standard EPIDs. Geometrical and optical transport parameters were varied to investigate their impact on imaging and dosimetry performance. Detection efficiency was most sensitive to variations in fibre length, achieving a peak value of 36% at 50 mm using 400 keV x-rays for the lengths considered. Increases in efficiency for longer fibres were partially offset by reductions in sensitivity. Removing the extra-mural absorber surrounding individual fibres severely decreased the modulation transfer function (MTF), highlighting its importance in maximising spatial resolution. Field size response and relative dose profile simulations demonstrated a water-equivalent dose response and thus the prototype's suitability for dosimetry applications. Element-to-element mismatch between scintillating fibres and underlying photodiode pixels resulted in a reduced MTF for high spatial frequencies and quasi-periodic variations in dose profile response. This effect is eliminated when fibres are precisely matched to underlying pixels. Simulations strongly suggest that with further optimisation, this prototype EPID may be capable of simultaneous imaging and dosimetry in radiotherapy.
机译:使用Geant4开发了新型电子门成像设备(EPID)的蒙特卡洛模型,并对其在放射治疗中的成像和剂量测定应用的性能进行了表征。 EPID的几何形状基于正在研究中的物理原型,并且包含塑料闪烁纤维阵列,代替标准EPID中的金属板/荧光屏。改变了几何和光学传输参数,以研究它们对成像和剂量测定性能的影响。检测效率对纤维长度的变化最敏感,对于所考虑的长度,使用400 keV X射线在50 mm处达到36%的峰值。较长光纤的效率提高被灵敏度的降低部分抵消了。去除围绕单个光纤的壁外吸收器会严重降低调制传递函数(MTF),从而突出显示其在最大化空间分辨率方面的重要性。场大小响应和相对剂量分布模拟显示了水等效剂量响应,因此原型适用于剂量测定应用。闪烁纤维和下面的光电二极管像素之间的元素到元素不匹配导致高空间频率和剂量分布响应的准周期变化的MTF降低。当光纤与下面的像素精确匹配时,可以消除这种影响。模拟强烈表明,通过进一步优化,该原型EPID可能能够在放射治疗中同时进行成像和剂量测定。

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