Pregabalin (PGB) is an antiepileptic drug that is also approved for neuropathic pain and for the treatment of generalized anxiety disorder (GAD) [1,3,8,9]. PGB is a GABA analogue that is reported to have mild side effects including transient dizziness, somnolence, dry mouth and ataxia [14]. Edemas are reported to occur in up to 8 % of the treated patients but only in higher doses [7]. In the literature to date, there are only two reports on PGB-related edema [12,15], one of them caused by withdrawal of the drug [12] and one observed with medium dosages of PGB [15]. The authors of the latter case report conclude, however, that edema with PGB treatment may be self-limited, transient and therefore not frequently found.
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