SYNTHESIS AND ANTI-INFLAMMATORY ACTIVITY OF 3,1-BENZOXAZIN-4(3H)-ONES AND N-ACYL-5-IODOANTHRANILIC ACID AMIDES

摘要

A series of new 3,1-benzoxazin-4(3H)-ones were synthesized and N-acyl-5-iodoanthranilic acid amides derived from them were obtained in a search for new biologically active derivatives of anthranilic acid. The anti-inflammatory activity of these compounds was evaluated. It is established that these classes of compounds are promising for further research on biologically active substances possessing anti-inflammatory activity.