Infectious and inflammatory skin diseases in children with HIV infection and their relation with the immune status--evaluation of 127 patients.

摘要

Human immunodeficiency virus infection causes changes in the immune system and disease evolution can be partially measured by levels of T CD4(+) lymphocytes. Knowledge of the chronology of skin disease in relationship to the immune status of the patient may help understand the pathogenesis of AIDS. One hundred twenty-seven children were prospectively evaluated for skin diseases and their relationship to immune status. Immunodeficiency in human immunodeficiency virus-infected children was correlated with infectious dermatoses whereas normal CD4(+) T lymphocyte levels was correlated with diseases mediated by hypersensitivity mechanisms.