The utility of dermatoscopy in the evaluation of xanthogranulomas.

摘要

The clinical differential diagnosis of a solitary, well-defined papule or nodule is extensive, and includes dermatofibroma, melanocytic nevus, xanthoma, neurofibroma,cyst, and xanthogranuloma, among other conditions (1). Despite their nonspecific clinical appearance (Fig. 1), xanthogranulomas can be correctly identified with the aid of dermatoscopy. The predominance of lipid-laden histiocytes in fully developed xanthogranulomas (2) renders the characteristic dermatoscopic findings, namely an orange-yellow background with subtle erythematous border, which has been compared with a setting sun (Fig. 2). "Clouds" of paler yellow areas, reported to represent collections of lipid-laden histiocytes located in the superficial dermis (3), may accompany the orange-yellow glow. Additional nonspecific dermatoscopic features that may be present include a subtle pigment network and whitish streaks indicative of foci of fibrosis.