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Endoscopic findings in children with obstructive sleep apnea: effects of age and hypotonia.

机译:阻塞性睡眠呼吸暂停患儿的内窥镜检查结果:年龄和肌张力降低的影响。

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摘要

Obstructive sleep apnea (OSA) syndrome is a common disorder among children and is often associated with significant morbidity. The causes of OSA are related to either fixed upper airway abnormalities such as adenotonsillar hypertrophy, or dynamic airway abnormalities such as laryngomalacia and pharyngeal wall collapse. The aim of the present study was to determine the prevalence of dynamic upper airway abnormalities, based on endoscopic findings, in normotonic and hypotonic children with polysomnographically documented OSA. The records of 39 consecutive children with OSA who underwent bronchoscopy (22 with normal tone, and 17 with hypotonia) were reviewed. The prevalence of dynamic defects among children with normal tone decreased with age. All 7 patients less than 1 year old had dynamic abnormalities (isolated or combined fixed/dynamic), compared to only 66% (6/9) of patients between 1-2 years old, and 17% (1/6) of children more than 2 years old. In contrast, dynamic abnormalities were very common among hypotonic children, independent of age. Since children with dynamic defects are less likely to respond to surgical treatments, it would be appropriate to identify these children prior to any intervention. Due to the higher frequency of dynamic defects in both infants (< 1 year) and hypotonic children, it may be appropriate to include endoscopy as part of the diagnostic evaluation of OSA in these subgroups.
机译:阻塞性睡眠呼吸暂停综合症(OSA)综合征是儿童中的常见疾病,通常与明显的发病率相关。 OSA的原因与固定的上呼吸道异常(如腺扁桃体肥大)或动态呼吸道异常(如喉软化和咽壁塌陷)有关。本研究的目的是根据内窥镜检查结果确定在多导睡眠图记录的OSA的正常和低渗儿童中动态上呼吸道异常的患病率。回顾了39例接受OSA支气管镜检查的儿童的记录(22例正常音调和17例低渗症)。正常音调儿童中动态缺陷的患病率随年龄的增长而降低。所有7位不到1岁的患者都有动态异常(孤立或固定/动态合并),而1-2岁之间的患者只有66%(6/9),而儿童中只有17%(1/6)超过2岁。相反,低渗儿童的动态异常非常普遍,与年龄无关。由于患有动态缺陷的儿童不太可能对手术治疗做出反应,因此在进行任何干预之前先确定这些儿童是适当的。由于婴儿(<1岁)和低渗儿童的动态缺陷发生频率较高,因此在这些亚组中将内窥镜检查作为OSA诊断评估的一部分是适当的。

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