Hepatitis C virus co-infection and sexual risk behaviour are associated with a high homocysteine serum level in HlV-in-fected patients

摘要

A better understanding of the true relationship or homocysteine with cardiovascular risk factors is needed. In the HIV population, increased homocysteine serum level is associated with sexual risk behaviour and hepatitis C virus coinfection. An association was found between higher homocysteine serum levels and: sexual HIV risk behaviour and hepatitis C virus co-infection in HIV-in-fected patients. From September 2007 until July 2008, in one of the HIV outpatient clinics of the Hospital General of Castellon in Spain, we enrolled all patients older than 18 years of age, except pregnant women, patients with creatinine serum levels > 2 mg/dl, and subjects who were taking vitamin supplements as all those circumstances have been demonstrated to influence homocysteine serum level.