Synthesis of 2-(2-arylethenyl)-5-arylfurans by regioselective palladium(0)-catalyzed coupling reactions of 2-(2-bromo-2-nitroethenyl)-5-bromofuran

摘要

The Suzuki reaction of 2-(2-bromo-2-nitroethenyl)-5-bromofuran, readily available from furfural, resulted in regioselective attack onto the furan moiety. The alkenyl moiety could be functionalized in a second Suzuki reaction.