Highly enantioenriched 2-azabenzonorbornenes from 7-azabenzonorbornadienes by asymmetric hydroboration-oxidation and tandem deoxygenation-rearrangement-electrophile trapping

摘要

3-exo-Substituted 2-azabenzonorbornenes are accessible from 7-azabenzonorbomadienes in good yields and high enantiomeric excess via asymmetric hydroboration-oxidation, followed by tandem deoxygenation-rearrangement-electrophile trapping and also provide access to substituted aminometbylindenes.