Detection and characterization of intermolecular multiple-quantum coherence NMR signals of IS (I = 1/2; S = 3/2) spin systems

摘要

Intermolecular multiple-quantum coherences (iMQCs) have some intrinsic properties different from conventional single-quantum coherences in solution NMR. In this paper, we extended our study to heteronuclear iMQCs in IS (I = 1/2, S = 3/2) spin systems. A sample of sodium chloride (NaCl) water solution was taken as an example. Heteronuclear COSY revamped by asymmetric Z-gradient echo detection (CRAZED) experiments were performed. One- and two-dimensional heteronuclear iMQC spectra were obtained. The quantum-mechanical treatment was used to deduce the signal expressions. Magic angle experiments validate that the signals are indeed from intermolecular dipolar interaction and insensitive to the imperfection of radio-frequency (RF) flip angles. Both experimental results and theoretical analysis indicate that heteronuclear CRAZED experiment allows coherence transfer from spin-3/2 nuclei to spin-1/2, and vice verse. Furthermore, the dependences of iMQC signal intensities on RF pulse flip angles follow the same rules as those for heteronuclear IS (I = 1/2, S = 1/2 or 1) spin systems.