Ferrocenyl-substituted Schiff base complexes of boron: Synthesis, structural, physico-chemical and biochemical aspects

摘要

Biological important complexes of boron(III) derived from 1-acetylferrocenehydrazinecarboxamide (L~1H), 1- acetylferrocenehydrazinecarbothioamide (L2H) and 1-acetylferrocene carbodithioic acid (L~3H) have been prepared and investigated using a combination of microanalytical analysis, melting point, electronic, IR, ~1H NMR and ~(13)C NMR spectral studies, cyclic voltammetry and X-ray powder diffraction studies. Boron isopropoxide interacts with the ligands in 1:1, 1:2 and 1:3 molar ratios (boron:ligand) resulting in the formation of coloured products. On the basis of conductance and spectral evidences, tetrahedral structures for boron(III) complexes have been assigned. The ligands are coordinated to the boron(III) via the azomethine nitrogen atom and the thiolic sulfur atom/enolic oxygen atom. On the basis of X-ray powder diffraction study one of the representative boron complex was found to have orthorhombic lattice, having lattice parameters: a = 9.9700, b = 15.0000 and c = 7.0000. Both the ligands and their complexes have been screened for their biological activity on several pathogenic fungi and bacteria and were found to possess appreciable fungicidal and bactericidal properties. Plant growth regulating activity of one of the ligand and its complexes has also been recorded on gram plant, and results have been discussed.