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Biological resurfacing for early osteoarthritis of the shoulder

机译:生物表面置换治疗肩部早期骨关节炎

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Young patients with degenerative shoulder disease are a therapeutic challenge. To try to delay a shoulder arthroplasty, biological interpositional arthroplasty has been proposed to provide a biologically active bearing surface that could eventually results in the formation of fibrocartilage, fibrous tissue, or hyaline cartilage. Anterior capsule, autogenous fascia lata, Achilles tendon allograft, lateral meniscus allograft, human dermis, and porcine small intestine submucosa have been used as interposition material, either alone or in combination with a hemiarthroplasty or humeral resurfacing procedure. Some investigators have reported favorable long-term results, although others have found this procedure unreliable. Several variables are unknown at present, such as the best biological resurfacing device, healing potential, possible antigenic responses, optimal fixation technique or position, aftercare restrictions. Further prospective studies with long follow-up are necessary to provide data that will help to define the role of biological glenoid resurfacing in young patients with glenohumeral arthritis.
机译:患有退行性肩部疾病的年轻患者是治疗上的挑战。为了试图延迟肩关节置换术,已经提出了生物介入关节置换术以提供具有生物活性的支承表面,该表面最终可能导致纤维软骨,纤维组织或透明软骨的形成。前囊,自体筋膜,跟腱同种异体,半月板异体半月板,人真皮和猪小肠粘膜下层已单独用作介入材料,或与半髋关节置换术或肱骨表面置换术结合使用。一些研究者报告了长期良好的结果,尽管其他研究者发现此程序不可靠。目前尚不知道几个变量,例如最佳的生物表面修复设备,愈合潜力,可能的抗原反应,最佳的固定技术或位置,术后护理限制。有必要进行长期随访的前瞻性研究,以提供数据,以帮助确定生物盂复位在年轻的盂肱型关节炎患者中的作用。

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