A gene for a new monogenic neurovascular migraine syndrome: a next step in unravelling molecular pathways for migraine?

摘要

Migraine is a multifactorial disorder in which both multiple genetic (estimated at up to 61%) and non-genetic factors are contributing to the disease risk (for review see 1). Unravelling its molecular basis will undoubtedly help to elucidate the underlying mechanisms for the migraine trigger threshold and may ultimately lead to novel prophylactic treatment targets (2)#