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A reduced model of pulsatile flow in an arterial compartment

机译:动脉腔内搏动流量的简化模型

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摘要

In this article we propose a reduced model of the input–output behaviour of an arterial compartment, including the short systolic phase where wave phenomena are predominant. The objective is to provide basis for model-based signal processing methods for the estimation from non-invasive measurements and the interpretation of the characteristics of these waves. Due to phenomena such that peaking and steepening, the considered pressure pulse waves behave more like solitons generated by a Korteweg–de Vries (KdV) model than like linear waves. So we start with a quasi-1D Navier–Stokes equation taking into account radial acceleration of the wall: the radial acceleration term being supposed small, a 2scale singular perturbation technique is used to separate the fast wave propagation phenomena taking place in a boundary layer in time and space described by a KdV equation from the slow phenomena represented by a parabolic equation leading to two-elements windkessel models. Some particular solutions of the KdV equation, the 2 and 3-soliton solutions, seems to be good candidates to match the observed pressure pulse waves. Some very promising preliminary comparisons of numerical results obtained along this line with real pressure data are shown.
机译:在本文中,我们提出了一种简化的动脉腔输入输出行为模型,包括以脉搏现象为主的短收缩期。目的是为基于模型的信号处理方法提供基础,以根据非侵入性测量进行估算并解释这些波的特征。由于出现峰值和变陡现象,所考虑的压力脉冲波的行为更像是Korteweg-de Vries(KdV)模型生成的孤子,而不是线性波。因此,我们从考虑壁的径向加速度的准一维Navier–Stokes方程开始:假设径向加速度项较小,则使用2阶奇异摄动技术来分离在边界层中发生的快速波传播现象。 KdV方程描述的时间和空间是由抛物线方程表示的缓慢现象所导致的,该方程导致了两个元素的风向标模型。 KdV方程的某些特定解(2和3孤子解)似乎是匹配观察到的压力脉搏波的良好候选者。显示了一些非常有希望的初步比较,这些结果是沿着这条线与实际压力数据获得的。

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