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Soil Cleanup Goal for Dioxin Using Probabilistic Risk Assessment Techniques

机译:使用概率风险评估技术的二恶英土壤净化目标

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摘要

State regulators in Florida recently approved a first-of-its-kind probabilistic risk assessment (PRA) for determining an alternative residential Soil Cleanup Target Level (SCTL) for dioxin (32ng/kg TEQ). The default residential SCTL (7ng/kg TEQ) is based on a single, deterministic calculation with numerous conservative assumptions, resulting in an overly conservative value far beyond the regulatory mandate (i.e., 10(-6) increase in cancer risk). Conversely, this PRA used a Monte Carlo simulation to estimate risk for all members of a large population using a combination of scientific data and professional judgment, with final details developed during negotiations with regulators. The simulation parameters were defined probabilistically and reflect the ranges of values for the following exposure variables: body weight, exposure duration, exposure frequency, fraction from contaminated source, soil ingestion rate, and relative bioavailability. Other variable and uncertain parameters were treated deterministically per direction from the regulators. The state also required that a pre-supposed high-risk subpopulation be analyzed separate from the full receptor population. Despite the conservativeness of the alternative SCTL, this PRA represents a significant step toward more realistic estimates of human health risks caused by environmental contaminant exposure.
机译:佛罗里达州的监管机构最近批准了首例概率风险评估(PRA),用于确定二恶英(32ng / kg TEQ)的替代住宅土壤清洁目标水平(SCTL)。默认的住宅SCTL(7ng / kg TEQ)是基于具有许多保守假设的单一确定性计算得出的,其过度保守的价值远远超出监管规定(即致癌风险增加10(-6))。相反,该PRA使用蒙特卡洛模拟方法结合科学数据和专业判断力来估计大量人口中所有成员的风险,并在与监管机构的谈判中确定了最终细节。模拟参数的定义是概率性的,并反映以下暴露变量的值范围:体重,暴露持续时间,暴露频率,来自污染源的分数,土壤摄入率和相对生物利用度。在调节器的每个方向上确定性地处理了其他可变和不确定参数。该州还要求将假定的高风险亚人群与完整的受体人群分开进行分析。尽管SCTL的替代方法很保守,但PRA还是朝着更实际地估计由环境污染物暴露引起的人类健康风险迈出的重要一步。

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