Polarographic and Voltammetric Determination of Trace Amounts of 2-Aminoanthraquinone

摘要

2-Aminoanthraquinone(2-AA)is a genotoxic intermediate in the industrial synthesis of anthraquinone dyes.In this work,electroanalytical methods based on two-electron reduction of anthraquinone at mercury electrodes were developed for determination of micro-to nanomolar concentrations of this analyte in mixed aqueous-methanol media.Calibration plots obtained for differential pulse voltammetry and direct current voltammetry at a hanging mercury drop electrode exhibited a sigmoidal shape within the analyte's concentration range of(1-500)X10~(-7)mol L~(-1),presumably because of strong adsorption of the analyte at the electrode surface.Linearity of the calibration plots was achieved for higher concentrations of 2-AA at a conventional dropping mercury electrode using DC tast polarography and differential pulse polarography,with limit of quantitation of 4X10~(-6)mol L~(-1)in Britton--Robinson buffer(pH 6)-methanol mixture(1:1).Adsorption of 2-AA on the electrode surface enabled its determination at nanomolar concentrations(limit of quantitation 2.8 X10~(-9)mol L~(-1))using cathodic adsorptive stripping voltammetry in Britton-Robinson buffer(pH 2)-methanol mixture(99:1).