A Review of U.S. Patents in the Field of Organic Process Development Published During June and July 2008

摘要

The current review includes 22 patents from an initial list containing 264 that fitted the search criteria. In this collection there are five patents covering the production of antiepileptic drugs including three covering the drug gabapentin. One of these discloses a novel process for the synthesis of a key intermediate, a second covers a novel tannate salt of gabapentin, and the third describes a method of purifying the drug using ion-exchange resins.