Effect of oral Rosmarinus officinalis (Rosemary) on morphometries and histology of rat testes

摘要

Hamedi S, Mansourirad A., Effect of oral Rosmarinus officinalis (Rosemary) on morphometrics and histology of rat testes, Onl J Vet Res., 19(10): 684-688, 2015. Five groups of ten rats each were gavaged distilled water (controls) or 1ml rosemary extract in 50, 100, 150, and 200 mg/kg daily for 28d. At necropsy, testis were fixed in 10% buffered formalin and assessed microscopically for morphometric and histological changes. Data was analyzed by one-way ANOVA test. Compared with controls, 50-100mg/kg Rosemary extract increased numbers of seminiferous and leydig cells whereas 150-200 mg/kg decreased seminiferous cells. Rosmarinus officinalis may improve fertility in rats at lower doses but may be deleterious at higher doses.