Photochemical rearrangement of oxaziridines and itrones in the hexahydroindole series:A convenient synthetic route to synthetic route to1-azabicyclo[5.2.0]nonan-2-ones as novel RGD mimetics

摘要

Photolysis of oxaziridines a or nitrones b provides a convenient synthetic route to fused bicyclic lactams c adequately substituted on bot crysles A and B as scafolds for mimicking conformationally constrained #beta#-turn peptides as in the tripeptide RGD signaling motif of fibronectin.