Progress toward the Total Synthesis of Bafilomycin A_1: Stereoselective Synthesis of the C15-C25 Subunit by Additions of Nonracemic Allenylzinc Reagents to Aldehydes

James A. Marshall; Nicholas D. Adams

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Progress toward the Total Synthesis of Bafilomycin A_1: Stereoselective Synthesis of the C15-C25 Subunit by Additions of Nonracemic Allenylzinc Reagents to Aldehydes

机译：向总合成Bafilomycin A_1的进展：通过向醛中添加非外消旋烯丙基锌试剂的立体选择性合成C15-C25亚基。

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A highly stereoselective synthesis of the C15-C25 subunit (2) of bafilomycin A_1 (1) has been accomplished by a route utilizing additions of chiral nonracemic allenylzinc reagents to aldehydes.

机译：巴非霉素A_1（1）的C15-C25亚基（2）的高度立体选择性合成已经通过利用将手性非外消旋烯基锌试剂添加到醛中的途径完成。

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《Organic letters》 |2000年第18期|共4页
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James A. Marshall; Nicholas D. Adams;
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1. Progress toward the Total Synthesis of Bafilomycin A_1: Stereoselective Synthesis of the C15-C25 Subunit by Additions of Nonracemic Allenylzinc Reagents to Aldehydes [J] . James A. Marshall, Nicholas D. Adams Organic letters . 2000,第18期

机译：向总合成Bafilomycin A_1的进展：通过向醛中添加非外消旋烯丙基锌试剂的立体选择性合成C15-C25亚基。
2. Synthetic studies on bafilomycin A_1:stereoselective synthesis of the enantiopure C_1-C_(11) fragment [J] . Emmanuelle Queron, Robert Lett Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 2004,第23期

机译：bafilomycin A_1的合成研究：对映纯C_1-C_（11）片段的立体选择性合成
3. Total Synthesis of (+)-Lepadin B: Stereoselective Synthesis of Nonracemic Polysubstituted Hydroquinolines Using an RC-ROM Process [J] . Guillaume Barbe, Andre B. Charette Journal of the American Chemical Society . 2008,第42期

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Progress toward the Total Synthesis of Bafilomycin A_1: Stereoselective Synthesis of the C15-C25 Subunit by Additions of Nonracemic Allenylzinc Reagents to Aldehydes

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