Synthesis and biological screening of 1-(H)-3-N-{4'-[(4''-chlorophenyl) (phenyl) methyl amino] phenyl}-5~aryl-pyrazolinesand 2-amino-6-{4'-[(4''-chloro phenyl) (phenyl) methyl amino]phenyl}-4 -aryl-4H - pyran-3- carbonitriles

摘要

1-(H) 3-N-{4'-[(4"'-Chlorophenyl) (phenyl) methyl amino] phenyl}-5-aryl-pyrazolines (5a-51) and 2-amino-6- {4'-[(4"'-chlorophenyl) (phenyl) methyl amino] phenyl}-4-aryl-4H-pyran-3-carbonitnles (6a-61) have been synthesized. The products have been assayed for their biological activity against Gram +ve, Gram -ve bacteria and fungi. Some of the compounds showed moderate activity in concentration 50 μg/ml.