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Copper and Zinc Serum Level in Patients Receiving Hemodialysis

机译:血液透析患者的铜和锌血清水平

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摘要

Decreased kidney function can accumulate trace elements. Increased trace elements can have toxic features. On the other hand, studies are showing that concentration of some trace elements could be decreased in chronic kidney disease patients as well.Because these patients are at risk for alterations of trace elements, we measured serum level of zinc and copper trace elements in hemodialysis patients and compare it with the control group. We analyzed the trace elements' copper and zinc concentrationin the whole blood of 52 ESRD patients who were treated with hemodialysis as case group and also of 52 age and sex matched healthy people as control group. Whole blood trace element concentration was determined by atomic absorption spectrometry. The serum concentrations of zinc and copper were significantly lower in case group compared to control group. The serum concentration of zinc and copper trace elements in end-stage renal failure patients is disturbed. Due to the discrepancy in findings of different studies, further studies in large scale are recommended to determine the serum concentration of trace elements in these patients.
机译:肾功能下降会积聚微量元素。痕量元素增加可能具有毒性。另一方面,研究表明慢性肾脏病患者也可以降低某些微量元素的浓度。由于这些患者存在微量元素改变的风险,因此我们测量了血液透析患者的血清锌和铜微量元素水平并与对照组进行比较。我们分析了52例接受血液透析治疗的ESRD患者全血中微量元素铜和锌的浓度,并以52名年龄和性别相匹配的健康人作为对照组。全血微量元素浓度通过原子吸收光谱法测定。与对照组相比,病例组的血清锌和铜浓度显着降低。终末期肾衰竭患者的血清锌和铜微量元素浓度受到干扰。由于不同研究结果的差异,建议进一步大规模研究以确定这些患者中微量元素的血清浓度。

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