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Radiological and clinical results following high-dose intensity-modulated radiotherapy in recurrent craniopharyngioma: A case report

机译:大剂量调强放射治疗复发性颅咽管瘤的放射学和临床结果:一例报告

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摘要

Craniopharyngiomas (CPs) are rare benign suprasellar tumors. The standard treatment for CP is complete surgical resection or partial resection followed by adjuvant radiotherapy (RT). Adjuvant RT is typically administered at a total dose of 54 Gy with 1.8 Gy/fraction. The current study reported the case of a young patient affected by recurrent craniopharyngioma, who was treated with irradiation subsequent to several surgical resections. Image fusion and intensity?modulated radiation therapy techniques were employed to deliver a high total dose (63 Gy with 2.1 Gy/fraction) with no severe acute toxicities recorded. At the 6?year follow?up, no radiological or clinical signs of disease progression or late sequelae were observed.
机译:颅咽管瘤(CPs)是罕见的良性鞍上肿瘤。 CP的标准治疗是完全手术切除或部分切除,然后进行辅助放疗(RT)。辅助剂RT通常以54 Gy的总剂量和1.8 Gy /次的剂量给药。当前的研究报道了一名年轻的复发性颅咽管瘤患者,该患者在多次手术切除后接受了放射治疗。影像融合和强度调制放射治疗技术用于提供高总剂量(63 Gy,2.1 Gy /馏分),未记录到严重的急性毒性。在6年的随访中,未观察到疾病进展或后遗症的放射学或临床体征。

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