The role of soluble CD40L in immunosuppression.

摘要

We have recently performed the first comprehensive study of the potentialimmunosuppressive role of soluble CD40L (sCD40L). In addition, we demonstratedthat serum sCD40L can potentially be used as an indicator of response toanticancer therapy, and/or to better identify those patients who would have best chances to benefit from tumor-targeting vaccines or other therapeutic modalities.