N-Hetaryl-2-cyanoacetamides in the Synthesis of Substituted (E)-N-Hetaryl-2-cyanoacrylamides, (E)-N-Alkyl-N-hetaryl-2-cyanoacrylamides, and 6-Amino-2-oxo-4-phenyl-1-(pyridin-2-yl)-1,2-dihydropyridine-3,5-dicarbonitriles

摘要

Knoevenagel condensation of N-hetaryl-substituted cyanoacetamides with aldehydes gave the cor-responding (E)-N-hetaryl-2-cyanoacrylamides which were converted into (E)-N-alkyl-N-hetaryl-2-cyanoacryl-amides and 6-amino-2-oxo-4-phenyl-1-(pyridin-2-yl)-1,2-dihydropyridine-3,5-dicarbonitriles. The structure of (E)-N-(pyridin-2-yl)-2-cyano-3-phenylprop-2-enamide was determined by X-ray analysis.