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Pheochromocytoma in pregnancy: a case report and review of literature

机译:孕妇嗜铬细胞瘤:一例报道并文献复习

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摘要

Hypertension is atommon problem in pregnancy that can result in significant maternal and fetal morbidity and mortality. The common causes include pre-eclampsia, gestational hypertension and essential hypertension. Although phaeochromocytoma is a rare cause of hypertension in pregnancy, it can lead to potentially life-threatening cardiovascular complications for the mother and increased fetal mortality if left undiagnosed and untreated. The diagnosis can be confirmed by measurement of plasma and urinary catecholamines and their metabolities followed by radiological localization of the tumour. Surgical resection of the tumour after adequate pre-operative control of hypertension using sequential alpha- followed by beta-blockers is the definitive treatment. In pregnancy, depending on the gestation at which diagnosis is made, the optimal timing for surgery is during the late first or early second trimester. When the pregnancy is more advanced, medical management followed by combined caesarean section and tumour resection closer to term is preferred.
机译:高血压是怀孕中的atommon问题,可导致母婴严重发病和死亡。常见原因包括先兆子痫,妊娠高血压和原发性高血压。尽管嗜铬细胞瘤是妊娠高血压的罕见原因,但如果不加以诊断和治疗,它可能导致母亲潜在的威胁生命的心血管并发症并增加胎儿死亡率。可以通过测量血浆和尿儿茶酚胺及其代谢物,然后对肿瘤进行放射学定位来确定诊断。明确的治疗方法是采用序贯的α-受体阻滞剂和β-受体阻滞剂对高血压进行充分的术前控制后,手术切除肿瘤。在怀孕期间,取决于进行诊断的妊娠,手术的最佳时机是在妊娠晚期或妊娠中期。当妊娠更晚期时,最好进行药物治疗,然后再进行剖腹产和肿瘤切除术相结合,以接近足月。

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