CD95/Fas in the brain--not just a killer.

Beier CP; Schulz JB

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CD95/Fas in the brain--not just a killer.

机译：CD95 / Fas在大脑中-不只是杀手。

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Although CD95 (Fas/Apo-1) has long been known to be broadly expressed in the brain, its function has remained enigmatic. In this issue of Cell Stem Cell, Corsini et al. (2009) now show that CD95 serves as a potent activator of neurogenesis in both the healthy and injured brain.

机译：尽管早就知道CD95（Fas / Apo-1）在大脑中广泛表达，但其功能仍然令人迷惑。在本期《细胞干细胞》中，Corsini等人。（2009年）现在显示CD95在健康和受伤的大脑中都可以作为有效的神经发生激活剂。

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《Cell stem cell》 |2009年第2期|共3页
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Beier CP; Schulz JB;
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正文语种 eng
中图分类细胞生物学;
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1. CD95/Fas in the brain--not just a killer. [J] . Beier CP, Schulz JB Cell stem cell . 2009,第2期

机译：CD95 / Fas在大脑中-不只是杀手。
2. T-cell factor (TCF/LEF1) binding elements (TBEs) of FasL (Fas ligand or CD95 ligand) bind and cluster Fas (CD95) and form complexes with the TCF-4 and b-catenin transcription factors in vitro and in vivo which result in triggering cell death and/or cell activation [J] . Liu Xia, Huang Yuwei, Zhang Yuanyuan, Cellular and Molecular Neurobiology . 2016,第6期

机译：FasL（Fas配体或CD95配体）的T细胞因子（TCF / LEF1）结合元件（TBEs）在体外和体内与Fas（CD95）结合并成簇，并与TCF-4和b-catenin转录因子形成复合物，导致触发细胞死亡和/或细胞活化
3. Immunohistochemical characterization of Fas (CD95) and Fas Ligand (FasL/CD95L) expression in the injured brain: relationship with neuronal cell death and inflammatory mediators. [J] . Grosjean MB, Lenzlinger PM, Stahel PF, Histology and histopathology . 2007,第3期

机译：Fas（CD95）和Fas Ligand（FasL / CD95L）在受伤的大脑中表达的免疫组织化学表征：与神经元细胞死亡和炎症介质的关系。
4. Modulation of CD95 (APO-1/Fas)-induced hepatocyte death by NO [C] . P. R. GALLE, D. STRAND, Z. SU, International Symposium on the Maillard Reaction . 2002

机译：CD95（APO-1 / Fas）的调节 - 诱导肝细胞死亡
5. Roles of cellular FLICE-inhibitory protein (c-FLIP) and PI3K/Akt in Fas (CD95)-induced NF-kappaB activation and apoptosis through death effector domains. [D] . Lu, Bin. 2005

机译：细胞FLICE抑制蛋白（c-FLIP）和PI3K / Akt在Fas（CD95）诱导的NF-κB活化和细胞凋亡中通过死亡效应域的作用。
6. Differential expression of Fas receptors (CD95) and Fas ligands (CD95L) in HIV infected and exposed uninfected children in Cameroon versus unexposed children [O] . Béatrice Dambaya, Céline Nguefeu Nkenfou, Georgia Ambada, 2019

机译：喀麦隆未接触艾滋病毒的儿童和未接触艾滋病毒的儿童中Fas受体（CD95）和Fas配体（CD95L）的差异表达
7. Reactive Astrocytes Upregulate Fas (CD95) and Fas Ligand (CD95L) Expression But Do Not Undergo Programmed Cell Death During the Course of Anterograde Degeneration [O] . Ulrike Gimsa, Robert Nitsch 2014

机译：反应性星形胶质细胞上调Fas（CD95）和Fas配体（CD95L）表达，但在顺行变性过程中不会接受程序性细胞死亡

CD95/Fas in the brain--not just a killer.

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