Synthesis of 5-Alkyl(benzyl)idene-3-hydroxymethyl-2-thioxothiazolidin-4-ones

摘要

3-Hydroxymethylthiazolidinones are practically important compounds which are usually obtained by reaction of thiazolidin-4-ones with formaldehyde in organic solvents in the presence of a catalytic amount of an amine.The reaction is reversible,and in some cases the yields of the target products are low [1].