Reaction of Haloacrylic Acids with Phosphorus Nucleophiles

摘要

alpha-Chloroacrylic acid reacts with triphenylphosphine to give (E)-(2-carboxyvinyl)triphenylphosphonium chloride.The same reaction with beta-halomethacrylic acids yields,depending on the temperature,either (2-carboxypropenyl)triphenylphosphonium halides or their isomeric (2-carboxyallyl)triphenylphosphonium halides.The possibility of "unusual" isomerization of the first compounds to the latter is shown.Synthesis of 1,2(diphenylphosphinoyl)ethane from alpha-chloroacrylic acid is carried out.