Partition Constants of alpha-Aminophosphonates in Two-Phase Aqueous-Organic Solvent Systems

摘要

Two-phase potentiometric titration was used to determine partition constants for a series of alpha-aminophosphonates (RO)_2P(O)CH_2NR~1R~2 [R = Alk (C_2-C_5),R~1,R~2 = Me,Et,(CH_2)_5] between water and organic solvents,such as chloroform,carbon tetrachloride,toluene,octane,n-octanol,nitrobenzene,o-xylene,and cyclohexane.Correlations between the partition constants and the number of carbon atoms in substrate molecules were obtained.Solvent effects on partition constants were discussed,and solution parameters of a-aminophosphonates were calculated.