Silylation of Hydroxyalkylidenediphosphonic Acids as an Effective Method of Their Purification

摘要

As known, the silylation of hydroxyl-containing organic compounds significantly increases their volatility. Therefore it seemed interesting to study the silylation of some hydroxyalkylidenediphosphonic acids and to test the possibility of using this procedure for a deep purification of these substances. Alkylidenediphosphonic acids are widely used as complex forming agents in chemistry and medicine [1], andsignificant difficulties are often met while isolating them in a pure state [2, 3].