Synthesis of 2-Substituted-1,3-oxazolidines under Microwave Irradiation

摘要

2-Substituted-1,3-oxazolidines still remain actively studied nitrogen-containing heterocycles due to their effective application in medicine,agriculture,and polymer and paint and varnish industry [1-2].Among fairly few synthetic approaches to 1,3-oxazolidines,heterocyclization heterocyclization of vicinal amino-alcohols with various aldehydes and ketones occupies a special place.Depending on the activity of the starting reagents,the reaction time varies from 4 to 12 h.The yields of the target products are 65-95% [3-5].