Sinteza si caracterizarea unor noi N1-[(arilsulfonil)benzoil]-N4-3-metoxifenil-tiosemicarbazide si a produsilor lor de ciclizare dehidratanta

摘要

In the reaction of 4-(4-X-phenylsulfonyl)-benzoic acid hydrazides 1 with 3-methoxyphenyl isothiocyanate the N'-[4-(4-X-phenylsulfonyl)benzoyl]-N4-beta-methoxyphenyl)-thiosemicarbazides 2 were obtained.Cyclization of these compounds in presence of 8% NaOH led to formation of 5-[4-(4-X-phenylsulfonyl)phenyl]-4-beta-methoxyphenyl)-4H-1,2,4-triazole-3-thiols 3.Cyclization of the same acylthiosemicarbazides 2 in acidic medium to 1,3,4-thiadiazoles deriuatives failed.The structures of the new compounds were confirmed by IR,UV,~1H-NHR,~(13)C-NMR spectra and elemental analysis.