Reaction of (E)-1,14-trichloro-3-nitrobut-2-ene with amines: diastereoselective synthesis of N-substituted α-trichloromethyl-β-nitroamines

摘要

The addition of primary and secondary amines to (E)-1,1,1-trichloro-3-nitrobut-2-ene proceeded diastereoselectively and led to a number of new N-substituted α-trichloromethyl-β-nitroamines, whose stereochemistry was confirmed by X-ray crystallography and NMR spectroscopy.