Diastereomeric P*-mono- and P*,P*-bidentate diamidophosphite ligands based on 1,4:3,6-dianhydro-D-mannitol in asymmetric metalloeomplex catalysis

摘要

Synthesis of diastereomeric mono- and bidentate diamidophosphites bearing P*-stereo-centers and phosphabicyclo[3.3.0]octane backbone and their coordination with rhodium(I) and palladium(II) are considered. Their use in Rh-catalyzed asymmetric allylation allowed one to achieve 87% ee values and the use in Rh-catalyzed asymmetric hydrogenation gave up to 98% ee.