Novel bivalent spermine-based neutral neogalactolipids for modular gene delivery systems

Ivanova E. A.; Filatov A. V.; Morozova N. G.; Zenkova M. A.; Maslov M. A.

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Novel bivalent spermine-based neutral neogalactolipids for modular gene delivery systems

机译：新型的基于二价精胺的中性新半乳糖脂用于模块化基因传递系统

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New bivalent spermine-based neutral neogalactolipids have been synthesized to develop effective modular gene delivery systems (MGDS) targeting hepatocyte asialoglycoprotein receptors. MGDS composed of new neogalactolipids, cationic gemini-amphiphile, and DOPE were agglutinated in the presence of lectin RCA(120) and provided efficient delivery of fluorescently-labeled oligodeoxyribonucleotides into HepG2 cells.

机译：已经合成了新的基于二价精胺的中性新半乳糖脂，以开发针对肝细胞去唾液酸糖蛋白受体的有效模块化基因递送系统（MGDS）。在凝集素RCA（120）存在下凝集由新的新半乳糖脂，阳离子双生双亲物和DOPE组成的MGDS，并提供将荧光标记的寡脱氧核糖核苷酸有效递送到HepG2细胞中。

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《RSC Advances》 |2015年第113期|共5页
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Ivanova E. A.; Filatov A. V.; Morozova N. G.; Zenkova M. A.; Maslov M. A.;
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1. Novel bivalent spermine-based neutral neogalactolipids for modular gene delivery systems [J] . Ivanova E. A., Filatov A. V., Morozova N. G., RSC Advances . 2015,第113期

机译：新型的基于二价精胺的中性新半乳糖脂用于模块化基因传递系统
2. Self-assembled ternary complexes of neutral liposomes, deoxyribonucleic acid, and bivalent metal cations. Promising vectors for gene transfer? [J] . P. Bruhi, M. Pisani, A. Amici, Applied Physics Letters . 2006,第7期

机译：中性脂质体，脱氧核糖核酸和二价金属阳离子的自组装三元复合物。有望用于基因转移的载体？
3. Immunomodulation of bivalent Newcastle disease DNA vaccine induced immune response by co-delivery of chicken IFN- gamma and IL-4 genes. [J] . Sawant P. M., Verma P. C., Subudhi P. K., Veterinary Immunology and Immunopathology . 2011,第1a2期

机译：二价新城疫DNA疫苗的免疫调节通过共同递送鸡IFN-γ和IL-4基因诱导免疫应答。
4. Niosomes Containing Spermine-Based Cationic Lipid with Different Linkers for siRNA Delivery [C] . Supusson Pengnam, Praneet Opanasopit, Theerasak Rojanarata International conference and exhibition on Pharmaceutical Sciences and Technology . 2019

机译：含有基于精氨酸的阳离子脂质的定期组织，具有不同的链接剂，用于siRNA递送
5. The effects of the repeated delivery of neutral stimuli to peers on the acquisition of the neutral stimuli as conditioned reinforcers for the preschool students who delivered them. [D] . Oblak, Mara Katra. 2010

机译：反复向同伴传递中性刺激对获得中性刺激的影响，这些刺激是为传递这些条件的学龄前儿童提供的条件性增强剂。
6. Self-Assembled Lipoplexes of Short Interfering RNA (siRNA) Using Spermine-Based Fatty Acid Amide Guanidines: Effect on Gene Silencing Efficiency [O] . Abdelkader A. Metwally, Ian S. Blagbrough 2011

机译：使用基于精胺的脂肪酸酰胺胍的短干扰RNA（siRNA）的自组装脂质体：对基因沉默效率的影响。
7. Toward advanced modular drug and gene delivery system [O] . Saeed Aram Omer 100

机译：走向先进的模块化药物和基因传递系统

Novel bivalent spermine-based neutral neogalactolipids for modular gene delivery systems

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