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Radiolysis of selected antibiotics and their toxic effects on various aquatic organisms

机译:选定抗生素的放射分解及其对各种水生生物的毒性作用

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This study was conducted to investigate the decomposition of three y-irradiated antibiotics(e.g.,tetracycline,sulfamethazine,and lincomycin)and to compare the toxic effects on Daphnia magna.Vibrio fischeri,and Pseudokirchneriella subcapitata.The median cell growth inhibition concentrations(IC_(50))of tetracycline,lincomycin,and sulfamethazine for P.subcapitata dramatically increased(e.g.,toxicity decreased)after radiolysis.The results demonstrated that y-radiation treatment was efficient to decompose antibiotics and thereby their toxicity on P.subcaptitata remarkably decreased due to reduced parent compounds.
机译:本研究旨在研究三种γ射线辐射的抗生素(如四环素,磺胺二甲嘧啶和林可霉素)的分解,并比较其对巨大蚤(Daphnia magna),费氏弧菌和假单胞假单胞菌的毒性作用。中值细胞生长抑制浓度(IC_( (50))四环素,林可霉素和磺胺二甲嘧啶对人头疟原虫的分解作用显着增加(例如,毒性降低)。结果表明,γ射线辐射处理能够有效分解抗生素,因此其对人头恶性疟原虫的毒性显着降低,原因是还原母体化合物。

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