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Asthma in the elderly: underperceived, underdiagnosed and undertreated; a community survey.

机译:老年人哮喘:认识不足,诊断不足和治疗不足;社区调查。

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摘要

Bronchial asthma is now increasingly recognized in the elderly and is associated with significant morbidity and mortality. The aims of this study were two-fold: first, to assess the prevalence and, second, to evaluate diagnostic awareness, therapeutic management and patient perception of bronchial asthma among elderly patients in the community. From the age-sex register of an urban general practice in NE England, 2004 patients aged > 65 years were eligible for inclusion. Response to an initial screening questionnaire on respiratory symptomatology was 68% (n = 1362). Of these, 869 patients had respiratory symptoms: 390 voluntarily agreed to be evaluated further including assessment of airway physiology. In this group 369/390 had obstructive spirometry and, of these, 95 patients fulfilled clinical and physiological criteria of bronchial asthma. Prevalence of asthma within this age cohort was minimally and rather crudely assigned at 4.5% (95/2004). Among the 95 patients so-defined patients with asthma [age 70 +/- 8 years (mean +/- SD), FEV1 = 0.96 +/- 0.41, 33 male, 75 life-long non-smokers], subjective awareness, perception and attribution of pulmonary symptoms were poor. Further, despite tangible evidence of reversible and significant airflow limitation, only 21 were receiving inhaled glucocorticoid therapy (median daily dose 400 micrograms). Asthma in the elderly remains poorly perceived, poorly recognized and suboptimally treated. These findings are particularly apposite in the light of current epidemiological trends in asthma mortality and morbidity in elderly age cohorts.
机译:现在,老年人越来越认识到支气管哮喘,它与明显的发病率和死亡率有关。这项研究的目的有两个:第一,评估社区中老年患者的患病率,第二,评估对支气管哮喘的诊断意识,治疗管理和患者知觉。根据英格兰东北部城市常规医疗的年龄性别登记,2004年≥65岁的患者符合纳入条件。初步筛查问卷对呼吸系统症状的反应为68%(n = 1362)。其中,有869位患者有呼吸道症状:390位自愿同意接受进一步评估,包括评估气道生理。在该组中,369/390的肺活量计阻塞,其中95例符合支气管哮喘的临床和生理标准。在这个年龄组中,哮喘的患病率最低,而粗略估计为4.5%(95/2004)。在这95例哮喘明确患者中[年龄70 +/- 8岁(平均+/- SD),FEV1 = 0.96 +/- 0.41,33例男性,75岁终身不吸烟者],主观意识,感知并且肺部症状的归因不佳。此外,尽管有明显的证据表明可逆性和明显的气流受限,但只有21例接受了糖皮质激素的吸入治疗(每日平均剂量为400微克)。老年人的哮喘仍然难以感知,认识不佳且治疗效果欠佳。鉴于当前流行病学趋势,老年人队列中的哮喘死亡率和发病率,这些发现特别合适。

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