Synthesis, photoluminescent, antibacterial activities and theoretical studies of three novel coumarin and dihydropyran derivatives containing a triphenylamine group

摘要

Three new coumarin and dihydropyran derivatives (1-3) have been synthesized and their fluorescence behaviors in dichloromethane solutions were observed. The molecular structures of two representative compounds, 2 and 3, were confirmed by single crystal X-ray diffraction study. The three synthesized compounds were evaluated for their antibacterial activities against Staphylococcus aureus (S. aureus ATCC 29213), methicillin-resistant S. aureus (MRSA XJ 75302), vancomycin-intermediate S. aureus (Mu50 ATCC 700699), and USA 300 (Los Angeles County clone) in vitro by observing the minimum inhibitory concentration.