Multicomponent synthesis of C-tethered bispyrazol-5-ols using CeO2 nanoparticles as an efficient and green catalyst

摘要

CeO2 nanoparticles have been used as an efficient catalyst for the preparation of C-tethered bispyrazol-5-ols by pseudo five-component reaction of phenylhydrazine, acetylenedicarboxylates, and aromatic aldehydes at 70 A degrees C in water. The use of no hazardous organic solvent, as well as atom economy, short reaction times, little catalyst loading and high yields of products are some of the important features of this protocol.