AN EFFICIENT ENZYME CATALYZED METHODOLOGY FOR SYNTHESIS OF LEVULINATE ESTERS USING LIPASE AND SUPERCRITICAL CARBON DIOXIDE AS A GREEN BIOCATALYST AND SOLVENT

摘要

The present invention offers a green method for the synthesis of alkyl levulinate esters using biocatalyst lipase in solvent super critical carbon dioxide. This methodology possesses the advantages like greener biocatalyst and greener super critical carbon dioxide solvent which accomplish an eco-friendly aspect. This invention reports an efficient process for synthesis of various types of levulinate esters (alkyl and aryl) at 10-70 �C temperature for 1-24 h using biomass derived levulinic acid as a source. The process used is simple and efficient to obtain higher yield of product with easy work-up process. This method provided 40-99 % isolated yield of corresponding levulinate ester molecules.