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We thank Utman and Dhillon for their interest in our article.1 They expressed their concern that in some eyes in our cohort the intraocular pressure (IOP) increase, associated with intravitreal injection (0.05 mL) of bevacizumab, could have been of clinical significance in eyes with preexisting optic nerve head damage and provided results of a study to support their concern.2 However, that study was of a young (mean age, 28.9 years) myopic population and did not report a volume-dependent IOP increase. The average age of our cohort was 79.4 years. Therefore, it is absolutely inaccurate to extrapolate the results of triat study to our results. Moreover, Jonas et al,3 who studied a glaucoma-tous population, failed to find any morphologic optic disk changes after short-term increases in IOP.
机译:我们感谢Utman和Dhillon对本文的关注。1他们表示关注,在我们队列的某些人眼中,与贝伐单抗玻璃体内注射(0.05 mL)有关的眼内压(IOP)升高可能对先前患有视神经乳头损伤的眼睛,并提供了一项研究结果来支持他们的关注。2但是,该研究针对的是年轻人(平均年龄,28.9岁)近视人群,并且没有报告眼压升高与体积有关。我们队列的平均年龄为79.4岁。因此,将三合会研究的结果外推到我们的结果是绝对不准确的。此外,研究青光眼人群的Jonas等[3]在IOP短期增加后未发现任何形态学上的视盘改变。

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