Synthesis of furan-fused quinoxaline tetracyclic scaffolds via a three-component isocyanide-based reaction

摘要

A novel isocyanide-based three-component catalyst-free approach for synthesis of furan-fused quinoxaline tetracyclic frameworks in good yields via reaction of 6-hydroxybenzo[f]quinoxaline-2,3-dicarbonitrile, an aromatic aldehyde, and an isocyanide under reflux conditions in toluene is described.