Pathophysiological analysis of primary biliary cirrhosis focusing on choline/phospholipid metabolism

Kohjima Motoyuki; Enjoji Munechika; Yada Ryoko; Yoshimoto Tsuyoshi; Nakamura Tsukasa; Fukuizumi Kunitaka; Fukushima Nobuyoshi; Murata Yusuke; Nakashima Manabu; Kato Masaki; Kotoh Kazuhiro; Shirabe Ken; Maehara Yoshihiko; Nakajima Atsushi; Nozaki Yuichi; Honda Akira; Matsuzaki Yasushi; Nakamuta Makoto

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Pathophysiological analysis of primary biliary cirrhosis focusing on choline/phospholipid metabolism

机译：以胆碱/磷脂代谢为基础的原发性胆汁性肝硬化的病理生理分析

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Background & AimsInjury to biliary epithelial cells caused by disorders in bile composition may be the initial step in the pathogenesis of primary biliary cirrhosis (PBC). We therefore examined choline/phospholipid metabolism in livers of patients with PBC.

机译：背景与目的胆汁成分紊乱引起的胆管上皮细胞损伤可能是原发性胆汁性肝硬化（PBC）发病的第一步。因此，我们检查了PBC患者肝脏中的胆碱/磷脂代谢。

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《Liver international :》 |2015年第3期|共8页
作者
Kohjima Motoyuki; Enjoji Munechika; Yada Ryoko; Yoshimoto Tsuyoshi; Nakamura Tsukasa; Fukuizumi Kunitaka; Fukushima Nobuyoshi; Murata Yusuke; Nakashima Manabu; Kato Masaki; Kotoh Kazuhiro; Shirabe Ken; Maehara Yoshihiko; Nakajima Atsushi; Nozaki Yuichi; Honda Akira; Matsuzaki Yasushi; Nakamuta Makoto;
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正文语种 eng
中图分类内科学;
关键词
cholesterol; choline; MDR3; OCT1; phospholipids; primary biliary cirrhosis;

机译：胆固醇;胆碱;MDR3;OCT1;磷脂;原发性胆汁性肝硬化;

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专利

1. Pathophysiological analysis of primary biliary cirrhosis focusing on choline/phospholipid metabolism [J] . Kohjima Motoyuki, Enjoji Munechika, Yada Ryoko, Liver international : . 2015,第3期

机译：以胆碱/磷脂代谢为基础的原发性胆汁性肝硬化的病理生理分析
2. A Systems Model for Ursodeoxycholic Acid Metabolism in Healthy and Patients With Primary Biliary Cirrhosis [J] . RL OConnor‐Semmes, MA Young, P Zuo, CPT: Pharmacometrics & Systems Pharmacology . 2016,第8期

机译：健康和原发性胆汁性肝硬化患者熊去氧胆酸代谢的系统模型
3. Alterations and correlations of the gut microbiome, metabolism and immunity in patients with primary biliary cirrhosis [J] . Lv Long-Xian, Fang Dai-Qiong, Shi Ding, Environmental microbiology . 2016,第7期

机译：原发性胆汁性肝硬化患者肠道微生物组，代谢和免疫力的变化及其相关性
4. Bayesian Neural Network Applied in Medical Survival Analysis of Primary Biliary Cirrhosis [C] . Arsene Corneliu T.C., Lisboa Paulo J. Computer Modelling and Simulation (UKSim), 2012 UKSim 14th International Conference on . 2012

机译：贝叶斯神经网络在原发性胆汁性肝硬化医学生存分析中的应用
5. Predicting outcomes post liver transplantation in patients with primary biliary cirrhosis and primary sclerosing cholangitis. [D] . Zapatochny Rufo, Rebecca Jo. 2003

机译：预测原发性胆汁性肝硬化和原发性硬化性胆管炎患者肝移植后的结局。
6. The metabolism of 7-ethoxycoumarin in human liver microsomes and the effect of primary biliary cirrhosis: implications for studies of drug metabolism in liver disease. [O] . K W Woodhouse, H C Mitchison, E Mutch, 1985

机译：人肝微粒体中7-乙氧基香豆素的代谢和原发性胆汁性肝硬化的影响：对肝病药物代谢研究的意义。
7. The metabolism of 7-ethoxycoumarin in human liver microsomes and the effect of primary biliary cirrhosis: implications for studies of drug metabolism in liver disease. [O] . Woodhouse, K W, Mitchison, H C, Mutch, E, 1985

机译：人肝微粒体中7-乙氧基香豆素的代谢和原发性胆汁性肝硬化的影响：对肝病药物代谢研究的意义。

Pathophysiological analysis of primary biliary cirrhosis focusing on choline/phospholipid metabolism

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