A novel methylation derivatization method for O-18 analysis of individual carbohydrates by gas chromatography/pyrolysis-isotope ratio mass spectrometry

摘要

RationaleThe oxygen isotope ratio (O-18) of carbohydrates derived from animals, plants, sediments, and soils provides important information about biochemical and physiological processes, past environmental conditions, and geographical origins, which are otherwise not available. Nowadays, O-18 analyses are often performed on carbohydrate bulk material, while compound-specific O-18 analyses remain challenging and methods for a wide range of individual carbohydrates are rare.