enzymes that stop us getting our DNA in a twist

摘要

it would be all too easy for the double helical strands of the genetic material DNA to become tangled, with catastrophic results. But an army of enzymes prevents this happening by carefully regulating the replication, repair and recombination of DNA.In the 5 years of his BBSRC Fellowship, Dr Dale Wigiey has established a worldleading group studying the structure of these enzymes. This research is simultaneously providing new insights into some of the most fundamental of all biological mechanisms and new strategies for the design of novef antibiotics and anti-viral agents.