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Acetabular cartilage thickness: accuracy of three-dimensional reconstructions from multidetector CT arthrograms in a cadaver study.

机译:髋臼软骨厚度:尸体研究中从多探测器CT关节造影图重建三维重建的准确性。

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摘要

PURPOSE: To prospectively quantify the accuracy of hip cartilage thickness estimated from three-dimensional (3D) surfaces, generated by segmenting multidetector computed tomographic (CT) arthrograms by using direct physical measurements of cartilage thickness as the reference standard. MATERIALS AND METHODS: Four fresh-frozen cadaver hip joints from two male donors, ages 43 and 46 years, were obtained; institutional review board approval for cadaver research was also obtained. Sixteen holes were drilled perpendicular to the cartilage of four cadaveric acetabula (two specimens). Hip capsules were surgically closed, injected with contrast material, and scanned by using multidetector CT. After scanning, 5.3-mmcores were harvested concentrically at each drill hole and cartilage thickness was measured with a microscope. Cartilage was reconstructed in 3D by using commercial software. Segmentations were repeated by two authors. Reconstructed cartilage thickness was determined by using a published algorithm. Bland-Altman plots and linear regression were used to assess accuracy. Repeatability was quantified by using the coefficient of variation, intraclass correlation coefficient (ICC), repeatability coefficient, and percentage variability. RESULTS: Cartilage was reconstructed to a bias of -0.13 mm and a repeatability coefficient of + or - 0.46 mm. Regression of the scatterplots indicated a tendency for multidetector CT to overestimate thickness. Intra- and interobserver repeatability were very good. For intraobserver correlation, the coefficient of variation was 14.80%, the ICC was 0.88, the repeatability coefficient was 0.55 mm, and the percentage variability was 11.77%. For interobserver correlation, the coefficient of variation was 13.47%, the ICC was 0.90, the repeatability coefficient was 0.52 mm, and the percentage variability was 11.63%. CONCLUSION: Assuming that an accuracy of approximately + or - 0.5 mm is sufficient, reconstructions of cartilage geometry from multidetector CT arthrographic data could be used as a preoperative surgical planning tool.
机译:目的:为了前瞻性地量化由三维(3D)表面估计的髋关节软骨厚度的准确性,该精度是通过使用软骨厚度的直接物理测量作为参考标准对多探测器计算机断层扫描(CT)关节造影图进行分割而生成的。材料与方法:从两名年龄分别为43岁和46岁的男性供体中获得了四个新鲜冷冻的尸体髋关节。还获得了尸体研究机构审查委员会的批准。垂直于四个尸体髋臼的软骨(两个标本)钻了十六个孔。手术封闭髋关节囊,注入造影剂,并使用多探测器CT扫描。扫描后,在每个钻孔上同心地收获5.3毫米核,并用显微镜测量软骨厚度。使用商业软件以3D方式重建软骨。两位作者重复了细分。通过使用公开的算法确定重建的软骨厚度。使用Bland-Altman图和线性回归来评估准确性。通过使用变异系数,组内相关系数(ICC),可重复性系数和可变性百分比来量化可重复性。结果:软骨重建到-0.13 mm的偏差和+或-0.46 mm的重复性系数。散点图的回归表明多探测器CT倾向于高估厚度。观察者之间和观察者之间的重复性非常好。对于观察者内相关性,变异系数为14.80%,ICC为0.88,重复性系数为0.55 mm,变异百分比为11.77%。对于观察者之间的相关性,变异系数为13.47%,ICC为0.90,重复性系数为0.52 mm,变异百分数为11.63%。结论:假设大约±0.5 mm的精度已足够,从多探测器CT关节造影数据重建软骨几何形状可以用作术前手术计划工具。

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